This category covers compounds used to study cellular ageing and energy metabolism in the laboratory: mitochondrial function and membrane integrity, NAD+ metabolism and sirtuin activity, redox balance, telomere biology and cellular senescence, in cell culture and animal models.
The range includes NAD+, the coenzyme at the centre of cellular redox research; SS-31 (elamipretide), a mitochondria-targeted tetrapeptide that binds cardiolipin; Epithalon, a synthetic tetrapeptide studied in published literature for telomerase activity; MOTS-c, a mitochondria-derived peptide; 5-Amino-1MQ, a small-molecule NNMT inhibitor; FOXO4, a retro-inverso peptide studied for disrupting the FOXO4-p53 interaction in senescent-cell models; and reduced glutathione, the main intracellular antioxidant thiol.
Where a batch has been tested, its certificate of analysis is published in our lab reports with the batch number, test date and method. All products are supplied for in-vitro laboratory research only and are not for human or veterinary use.
A small-molecule inhibitor of the enzyme nicotinamide N-methyltransferase (NNMT). Studied in published in vitro and rodent research on NNMT activity, NAD+ salvage and adipocyte metabolism. Research use only.
- Purity tested
A synthetic tetrapeptide (Ala-Glu-Asp-Gly) modelled on epithalamin, a bovine pineal gland extract. Studied in published in vitro and animal research on telomerase activity, cellular senescence and melatonin secretion. Research use only.
- Purity tested
- Endotoxin tested
A tripeptide (γ-glutamyl-cysteinyl-glycine) and the main intracellular thiol antioxidant, supplied in lyophilised form. Studied in published in vitro research on redox balance, oxidative stress and enzymatic conjugation pathways. Research use only.
- Purity tested
A 16-amino-acid peptide encoded in mitochondrial DNA (12S rRNA region). Studied in published in vitro and rodent research on AMPK signalling, glucose metabolism and mitochondrial-nuclear communication. Research use only.
- Purity tested
- Endotoxin tested
Nicotinamide adenine dinucleotide, a coenzyme present in all living cells. Studied in published in vitro and animal research on cellular energy metabolism, DNA repair enzymes (PARPs) and sirtuin activity. Research use only.
- Purity tested
- Endotoxin tested
A mitochondria-targeted tetrapeptide (elamipretide) that binds cardiolipin in the inner mitochondrial membrane. Studied in published in vitro and animal research on cristae structure, electron transport chain organisation and mitochondrial bioenergetics. Research use only.
- Purity tested
- Endotoxin tested
A synthetic retro-inverso peptide (FOXO4-DRI) designed to interfere with the FOXO4-p53 interaction. Studied in published in vitro and mouse models of cellular senescence and senescent-cell apoptosis. Research use only.
- Purity tested