GHK-CU
A naturally occurring copper-binding tripeptide found in human plasma, extensively studied for wound healing, tissue regeneration, skin rejuvenation, and gene expression modulation across multiple organ systems. All presented information is based on scientific publications which can be found at the end of product description below.
Product Specifications
Description
All presented information is based on scientific publications which can be found at the end of product description below.
GHK-Cu (glycyl-L-histidyl-L-lysine copper complex) is a naturally occurring tripeptide first discovered in human plasma in 1973. Its biological effects are mediated through copper(II) ion binding and broad-spectrum gene expression modulation.
Research Highlights
1. Skin Rejuvenation โ Tightens skin, repairs barrier proteins, improves firmness and elasticity. Reduces fine lines, wrinkles, and photodamage.
2. Gene Expression โ Up/down-regulates numerous genes via Connectivity Map analysis. Activates collagen synthesis, angiogenesis, fibroblast activity.
3. Tissue Regeneration โ Promotes regeneration in lungs, bones, liver, and stomach lining. Stimulates collagen, elastin, and glycosaminoglycan synthesis.
4. Neuroprotection โ Alleviates neuronal apoptosis via miR-339-5p/VEGFA pathway.
5. Pulmonary Protection โ Inhibits pulmonary fibrosis and acute lung injury.
6. Antimicrobial โ GHK-Cu conjugates show antimicrobial activity in vitro.
References available upon request.
The product is intended for scientific research and development purposes only. Chemical substances shall not be used as a drug, medicine, active substance, medical aid, cosmetic product, a substance for production of a cosmetic product neither for human consumption that is any food or food supplement or otherwise similarly used on humans or animals. Intended only for in-vitro research, such as Receptor-ligand binding studies, Enzyme activity assays, Cell proliferation assays, Cell signaling assays, Epitope mapping, etc.
Research Use Only: The product is intended for scientific research and development purposes only. Chemical substances shall not be used as a drug, medicine, active substance, medical aid, cosmetic product, a substance for production of a cosmetic product neither for human consumption that is any food or food supplement or otherwise similarly used on humans or animals. Intended only for in-vitro research, such as Receptor-ligand binding studies, Enzyme activity assays, Cell proliferation assays, Cell signaling assays, Epitope mapping, etc.
๐ช๐บ EU & UK Shipped โข Free over โฌ300 โข 2-5 Business Days
Frequently asked questions
- GHK is a tripeptide (Gly-His-Lys) endogenously found in human plasma. GHK-Cu is its copper(II) complex (CโโHโโNโOโCu, MW โ 403.9 g/mol). Many of the biological activities reported in literature are attributed to the copper complex specifically, not the bare peptide.
- Each batch is HPLC-MS verified at โฅ99% purity. COA confirms identity, copper coordination, and lot details.
- Store lyophilised GHK-Cu at -20 ยฐC in a sealed vial protected from light โ the copper complex is sensitive to light and oxidation. Reconstituted solutions should be used promptly or stored short-term at 2-8 ยฐC in the dark.
- GHK-Cu is studied in dermal fibroblast culture, full-thickness wound healing models, hair follicle biology, and gene-expression-modulation research (transcriptomic studies suggest GHK-Cu influences thousands of human genes related to ECM, antioxidant defense, and inflammation).
- GHK-Cu is widely used in topical cosmetic formulations (regulated as cosmetics in many jurisdictions). Research-grade GHK-Cu supplied by Peptra Labs is for laboratory research only and is not approved as a systemic therapeutic.
