TB-500
A synthetic version of Thymosin Beta-4, central to tissue repair through actin regulation, angiogenesis promotion, and anti-inflammatory signaling across multiple organ systems. All presented information is based on scientific publications which can be found at the end of product description below.
Batch-level quality proof
Every research peptide is supplied as a sealed, clearly labelled vial. Batch-level CoA information and purity testing records are available online where applicable, not shipped as research paperwork in the parcel.
Clear label, lot traceability, protective packaging.
Listed report available for batch QY028. Purity shown: 99.67%.
Not for human or veterinary use, no protocol or dosing advice.
TB-500 CoA authority cluster
Use these pages to connect TB-500 product data, batch-level CoA information, RUO policy, and the preclinical research summary.
Product specifications
Description
All presented information is based on scientific publications which can be found at the end of product description below.
TB-500 is the synthetic form of Thymosin Beta-4, a naturally occurring peptide in virtually all tissue types. As a major actin-sequestering molecule, it plays fundamental roles in cell migration, blood vessel formation, and tissue repair. Research Highlights 1. wound repair research ā Enhanced cell migration, angiogenesis, collagen deposition, and tissue remodeling.
2. Cardiac Repair ā Activates cardiac progenitor cells, reduces scar formation, improves ventricular function post-MI.
3. Actin Regulation ā Primary intracellular G-actin sequestering peptide, modulating polymerization dynamics.
4. Anti-Inflammatory ā Downregulates inflammatory cytokines while promoting anti-inflammatory mediators.
5. Neurological ā Promotes oligodendrocyte differentiation and axonal regrowth after stroke/TBI.
6. Ocular Repair ā Promotes corneal wound repair research and reduces inflammation. References available upon request. The product is intended for scientific research and development purposes only. Chemical substances shall not be used as a drug, medicine, active substance, medical aid, cosmetic product, a substance for production of a cosmetic product neither for human consumption that is any food or food supplement or otherwise similarly used on humans or animals. Intended only for in-vitro research, such as Receptor-ligand binding studies, Enzyme activity assays, Cell proliferation assays, Cell signaling assays, Epitope mapping, etc.
Research Use Only: The product is intended for scientific research and development purposes only. Chemical substances shall not be used as a drug, medicine, active substance, medical aid, cosmetic product, a substance for production of a cosmetic product neither for human consumption that is any food or food supplement or otherwise similarly used on humans or animals. Intended only for in-vitro research, such as Receptor-ligand binding studies, Enzyme activity assays, Cell proliferation assays, Cell signaling assays, Epitope mapping, etc.
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Frequently asked questions
- TB-500 is a synthetic 17-amino-acid fragment derived from the central actin-binding region of Thymosin Beta-4 (TĪ²4), a 43-amino-acid protein found in most mammalian cells. The fragment retains the conserved LKKTET actin-binding motif. Molecular weight is approximately 2.0-2.2 kDa depending on terminal modifications.
- Batch-level CoA information is available where applicable and focuses on purity testing and lot details.
- Lyophilised TB-500 is stable at -20 Ā°C in a sealed, desiccant-protected vial for long-term storage. Reconstituted solutions are less stable - single-use aliquots are recommended to avoid freeze-thaw cycles, which can degrade the peptide.
- TB-500 (and full-length TĪ²4) has been studied in preclinical models of skin repair, corneal repair, myocardial infarction, skeletal muscle injury, and central nervous system damage. The mechanism of interest is G-actin sequestration and downstream effects on cell migration.
- No. TB-500 from Peptra Labs is supplied for laboratory research only and must not be used as a human or veterinary product.
